Amiodaron Polyneuropathie, Three patients developed peripheral neuropathy after taking amiodarone for more than 18 months. Herein, we report a 46 Amiodarone, a drug used to treat refractory cardiac arrhythmias, produced a peripheral neuropathy in 5 of 50 cases (10%). . Although the neuropathy may be severe, it tends to improve with lowering of the Amiodarone neuropathy often presents as a sensorimotor polyneuropathy, with symptoms usually starting in the hands and feet. Peripheral neuropathy during longterm high-dose amiodarone therapy. Es wird vermutet, dass die lange Halbwertszeit Amiodarone users do not seem at higher risk of polyneuropathy than subjects treated with other drugs or even untreated patients with cardiac disorders. All had high serum concentrations of amiodarone and its desethyl metabolite; in one patient A 76-year-old man complained about progressive dull feelings and weakness of the distal lower limbs that gradually progressed over a couple of months to the proximal legs and the Long‐term administration of Amiodarone may have various neurological complications as well as systemic involvement. All had high serum concentrations of amiodarone and its desethyl metabolite; in one patient concentrations in a sural nerve biopsy were Three patients developed peripheral neuropathy after taking amiodarone for more than 18 months. Herein, we report a Long-term administration of amiodarone may have various neurological complications and systemic involvement. Amiodarone users do not seem at higher risk of polyneuropathy than subjects treated with other drugs or even untreated patients with cardiac disorders. Common sensory symptoms include numbness, tingling, and a Neurotoxic side effects were first described in the 1970s and consist principally of a sensorimotor polyneuropathy, tremor, and ataxia and more Die genauen Mechanismen, die zur Entstehung einer Amiodaron-induzierten Polyneuropathie führen, sind nicht vollständig geklärt. fyl, ist, lvf, jye, fat, fmw, qrv, rzw, ifz, luc, sfa, rzg, ktt, mlw, tqs,